Endocrine Abstracts

Introduction: Some data suggest a favorable effect of glucagon-like peptide 1 (GLP1) on steato-hepatitis (SH) in type 2 diabetes. We report here a case of improvement of SH in a patient treated by liraglutide.Patients and methods: A 31-year-old woman presented type 2 diabetes. Her weight was 80 kg for 1.58 m (BMI=32 kg/m2). A treatment by liraglutide was initiated at 1.2 mg/day, percutaneously. A regular follow-up was performed with the record...

Introduction: Hyponatraemia constitutes the most common hydro-electrolytic abnormality and the determination of its cause is important for patient’s treatment, which can include the use of a pharmacological agent.Observation: A 78-year-old woman suffering from a lung adenocarcinoma presents a chronic hyponatraemia ranging from 114 to 123 mmol/l, which cannot be corrected by fluid limitation alone. Clinical and biological assessment leads to diagnose...

We present the case of a 36-year-old female with a focal neonatal hyperinsulinism diagnosed at birth in a context of hypoglycemia that was resistant to Diazoxide treatment. A subtotal pancreatectomy was performed and histology showed a focal hyperinsulinism. The mutation of ABCC8 was not searched at this point. The patient developed an insulin dependent diabetes at the age of 9 and required an insulin pump. In 2017 the patient was planning a pregnancy so she consulted a geneti...